The Outcome of Withholding Pharmacologic Treatment in Children with Acute ITP

Abstract

Background: ITP is a nonthreatening disorder disturbing children at any age but mostly below 5 years.

Objective: To evaluate the outcome of children with acute ITP who were not specified with any pharmacologic action and linked with those who were treated.

Patients and Methods: A prospective case- control   study was done between Jan.2002 to May 2016 at Mukalla children and Maternity Hospital and University Hospital for Children and Mother Health in Mukalla/ Hadhramout /Yemen,  where 20 children with acute ITP. the control group was 18 children given the conventional therapy. The identification and grouping of ITP were made according to the 2009 International Working Group criteria.

Results: In group A there were 11( 55%) boys and 9(45%) girls, while control group B there were 18 children 10 (55.5%) boys and 8 (44.5%) girls.   the ages were from 2 to 12 years. The mean age is 4.7 years with the median age at identification was 4r years. There was no statistical significant difference between both groups regarding outcome.

Conclusion: The recovery percentage has some relation with age at appearance and preliminary platelet count where younger children and those with platelet amount of <20000 /µL have better recovery percentage. There was no statistical significant difference between both groups regarding outcome.