Diyala Journal of Medicine <p style="text-align: justify;">Diyala Journal of Medicine (DJM) was established according to agreement of Ministry of Higher Education and Scientific Research-foundation of as per authorization letter Number 12c/2433 in 19th August 2010. Fellow up, Started to receiving different manuscripts in all fields of medicine such as clinical, basic, dentist, pharmacology and scientific original articles. Diyala Journal of Medicine usually Deal with articles closely related with clinical problem more common in Iraq and Middle East. Also considered is a periodic peer-reviewed journal published biannually by the College of Medicine in Diyala University. However, review articles of high standards will be considered Writing in English languages with Arabic abstract.</p> <p><span style="font-size: 20px; font-family: Times New Roman;"><span style="font-size: 20px; color: #17365d;">&nbsp;</span></span></p> College of Medicine - University of Diyala en-US Diyala Journal of Medicine 2219-9764 <p>All Rights Reserved.</p> Detection of Respiratory Syncytial Virus and Human Metapneumovirus in Children with Respiratory Tract Infection by Use Real Time Polymerase Chain Reaction <p>&nbsp;</p> <p><strong>Background:</strong> Respiratory tract illness is a major cause of morbidity and mortality among children, elderly and immunocompromised patients worldwide.</p> <p><strong>Objective:</strong> To determine the infection rate of respiratory syncytial virus and human metapneumovirus among children with respiratory tract infection in Baghdad city.</p> <p><strong>Patients and Methods:</strong> A cross sectional study was based on the processing of nasopharyngeal swabs from 150 children with acute respiratory tract infections, (81) males and (69)females; aged under five years old, who was admitted to Al-Imamin Al-Kadhimin Medical City and Pediatrics Protection Hospital in Baghdad during the period from December 2017 till April 2018. Nasopharyngeal swabs were collected from each participant and stored as frozen at -70 °C to use for RNA extraction and real time- polymerase chain reaction.</p> <p><strong>Results:</strong> Out of all these samples, 54 samples were positive for respiratory syncytial virus (36%) and human metapneumovirus (1.33%). The infection rate of respiratory syncytial virus is more common in males (57.41%) than females and in children ≤ one year (37.04%) also high frequency were noticed among patients live in an urban area (72.22%) (50%) respectively and winter. According to different clinical feature, fever, cough, and wheezing were more common.</p> <p><strong>Conclusion:</strong> The infection rate of respiratory syncytial virus was more than human metapneumovirus in children with respiratory tract infection using real time-PCR technique and the clinical manifestations were more common during respiratory syncytial virus and human metapneumovirus infection are&nbsp; cough, fever, wheezing.</p> Hala Luay Abduljabbar Areej Atiyah Hussein Iman M Aufi Qasim Sharhan Al-Mayah ##submission.copyrightStatement## 2018-12-20 2018-12-20 15 2 87 97 Evaluation of Delayed Puberty of Patients with Beta Thalassemia Major in –Diyala Governorate <p><strong>Background:</strong> The absence of secondary sexual characteristics are known complications in patients with beta thalassemia major.</p> <p><strong>Objective:</strong> Evaluation the effects of frequent blood transfusions on puberty in patients afflicted with beta thalassemia (β-thal) major.</p> <p><strong>Patients and Methods:</strong> Eighty patients with beta thalassemia major&nbsp; were categorized into two groups, 51 male and 29 female,and 40 normal individuals were chosen as a control group. The concentrations of the luteinizing hormone(LH), follicle stimulating hormone(FSH) in both genders,Estradiol in female and testosterone in male were evaluated in the sera of patients and controls by ELISA method.</p> <p><strong>Results:</strong> The mean concentrations of serum FSH ,LH, estradiol in female ,and testosterone in male showed&nbsp; highly significant decrease in patients with beta thalassemia major in comparison with control group. Hypogonadotropic hypogonadism was reported in 67.5% of all β-thalassemia patients(70.6% of male and 62.1% of female ).&nbsp;&nbsp;&nbsp;</p> <p><strong>Conclusion:</strong> Delayed puberty is caused by the effect of excess iron on the anterior&nbsp; lobe of pituitary gland.</p> Alaa A Mahmud Ali M Al-Gharawi Falah M Mustafa ##submission.copyrightStatement## 2018-12-20 2018-12-20 15 2 76 79 Prevalence of Recurrent Aphthous Ulceration in the Diyala Population <p><strong>Background:</strong> Recurrent aphthous stomatitis (RAS) are an inflammatory condition and most the common ulceration of the oral cavity of the patients that make them to ask dental practitioner consultation.&nbsp; most ulcers are associated with pain and heals spontaneously for some days.</p> <p><strong>Objective:</strong> To calculate the prevalence of this type of ulcers in diyala governorate among males and females and its association with stress and evaluate the independent issues correlated to this oral mucosal state.</p> <p><strong>Patients and Methods:</strong> A total of 80 patients who attended to the Baquba teaching hospital from April 2016 - April 2017 and fill the required questioner of this study which including age, gender, site, size of ulcer, stressed condition and smoking status in addition to other questions.</p> <p><strong>Results:</strong> The prevalence of RAS was 17.4%, the third decade of life were the most affected age. Males were affected more than females and the tongue were the most affected sites represents (25 %)of the cases. stress was the most causative factors of this lesions.</p> <p><strong>Conclusion:</strong> In diyala governorate, the Aphthus lesion is the main features of stress among males.</p> Mustafa Gheni Taher ##submission.copyrightStatement## 2018-12-20 2018-12-20 15 2 112 118